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For more information, please see full course syllabus of Microbiology
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Difference Measures of Disease

  • Introduction
    • How can we describe disease in human population?
      • Counts of individuals with disease
      • Determine sources of disease contamination
  • Case Study: Norovirus Outbreak in Restaurant, Michigan, 2006
  • Quantitative Measures to Determine Source of Illness
    • Attack rate to determine who became ill
    • Case-control analysis to determine food source
    • Construct possible hypotheses using suspect disease agents

Difference Measures of Disease

Lecture Slides are screen-captured images of important points in the lecture. Students can download and print out these lecture slide images to do practice problems as well as take notes while watching the lecture.

  • Intro 0:00
  • Introduction 0:16
    • What is the Extent of Disease?
    • Who is at Risk for the Disease?
    • How is Disease Transmitted?
    • How is Disease Defined?
  • Counts 2:17
    • Assessment
    • Example of Tuberculosis Count
  • Counts of Influenza Positive Tests 4:02
  • Counts of AIDS Cases 5:58
  • Example of a Food Outbreak Investigation 8:01
    • Steps Public Health Investigators Follow to Determine Cause of Illness
    • Identifying the Source
    • Example
  • Potential Sources of Contamination 9:44
    • Production
    • Farms
    • Distribution
    • Retail Establishments
    • Restaurant Example
  • Food Borne Outbreak Investigation Steps 11:43
    • Determining if an Outbreak is Occurring
    • Defining Signs and Symptoms
    • Hypothesis
    • Collect Data and Test Hypothesis
    • Not Finding Associations
    • After Finding Pathogen, You Can Conduct Intervention to Remove Contaminated Food
    • Determine the Source
    • Clear Outbreak When All Contamination is Gone
  • Case Study: Norovirus Outbreak Michigan Jan-Feb, 2006 14:34
  • Norovirus 16:14
    • Infects All Ages
    • Cause Infection Throughout the Year But There's a Peak in Time
    • Recognizing Outbreaks of Norovisur Infection
  • Cases of Norovirus Over Time 18:42
  • Attack Rate 19:24
    • Definition
    • Restaurant Example
  • Attack Rate by 3 Hour Time Intervals 22:52
  • Patrons Who Became Ill 23:35
  • Case Control Analysis to Determine Food Source 24:21
  • Attack Rate 25:58
  • Food Outbreak Measures 26:16
    • Compute the Denominator
    • Compute Attack Rate During Certain Time Period
    • Construct Possible Hypotheses
    • Conduct Case-Control Analysis with Odds Ratio
  • Example 1 29:47
  • Example 2 34:55
  • Example 3 36:51