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Tumor Immunology

  • Tumor Immunology Introduction
    • Examples of microbes inducing tumor development
  • Overview of Tumor Immunology
  • Immune Surveillance and Escape
  • Malignant Transformation
      • Progression of benign to malignant
      • Carcinogenesis
  • Tumor Antigens
  • Tumors and Immunosuppression
  • Tumor Immunotherapies

Tumor Immunology

Lecture Slides are screen-captured images of important points in the lecture. Students can download and print out these lecture slide images to do practice problems as well as take notes while watching the lecture.

  1. Intro
    • Antibodies Surrounding Tumor
      • Introduction to Tumor Immunology
      • Overview of Tumor Immunology
      • Immune Surveillance Theory and Escape
      • Malignant Transformation
      • Tumor Growth Over Time
        • Malignant Transformation
        • Progression of Benign to Malignant
          • Micro-Induced Carcinogenesis
          • Examples of Malignant Transformation
            • Tumor Antigens
            • Tumors in an Immunosuppressed Host
            • Tumor Immunotherapies
            • Inflammation and Cancer
            • Bacteria, Inflammation, and Cancer
              • Example 1
                • Example 2
                  • Example 3
                    • Example 4
                      • Intro 0:00
                      • Antibodies Surrounding Tumor 0:40
                      • Introduction to Tumor Immunology 1:22
                        • Human Papilloma
                        • Hepatitis B
                        • Helicobacter Pylori
                        • Immunology
                      • Overview of Tumor Immunology 4:17
                        • Immune Surveillance Theory
                        • Malignant Transformation
                        • Immune Reactivity to Tumors
                        • Tumor Antigens
                        • Tumor Immunotherapies
                        • Inflammation and Cancer
                      • Immune Surveillance Theory and Escape 4:59
                        • Amount of Antigen Expressed is Too Low
                        • Tumor Sheds Antigens That Block Antibodies and T-Cells from binding to the Tumor
                        • Tumor Does Not Express Immunogenic Antigens
                        • Tumor Does Not Express MHC Antigens
                        • Tumor May Secrete Immunosuppressive
                        • Hallmark of a Cancer Cell is Proliferation That is Dysregulated
                      • Malignant Transformation 7:39
                        • One Way to Cause Growth Regulations
                        • Mutations Can Alter the Cellular Machinery Leading to Up Regulation of Oncogenes
                        • Mutations Can Alter the Cellular Machinery Leading to Down Regulation of Tumor Suppressor Genes
                      • Tumor Growth Over Time 9:42
                      • Malignant Transformation 10:46
                        • Benign
                        • Malignant
                      • Progression of Benign to Malignant 12:35
                      • Micro-Induced Carcinogenesis 13:40
                        • Initiation Promotion Progression Model
                      • Examples of Malignant Transformation 14:53
                      • Tumor Antigens 15:46
                        • Tumor Must Express Antigens That the Immune System Recognizes as Foreign
                        • Immune Reactivity to Tumors
                        • Tumor Antigens
                        • Tumor Immunotherapies
                        • Tumorigenesis Secretes Chemical Signals That Change Gene Expression
                        • Gene Expression Leads To The Following
                      • Tumors in an Immunosuppressed Host 18:48
                        • HIV and AIDS
                        • Transplant Patients
                        • Epstein-Barr Virus
                        • Malaria
                      • Tumor Immunotherapies 20:45
                        • Active Therapy
                        • Passive Therapy
                      • Inflammation and Cancer 24:05
                        • Chronic Inflammation
                        • Inflammation as a Response to Cancer
                        • Neoplastic Cells Induce an Inflammatory Immune System
                      • Bacteria, Inflammation, and Cancer 25:59
                      • Example 1 27:46
                      • Example 2 29:21
                      • Example 3 30:25
                      • Example 4 31:28