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For more information, please see full course syllabus of Microbiology
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Lecture Comments (3)

2 answers

Last reply by: stefania markou
Mon Dec 15, 2014 9:44 PM

Post by stefania markou on December 15, 2014

Dr Carpenter ,
on Microbial Genetics lecture, the slide on Germline Mutation and Evolutionary Biology, it states that only germ cell mutations are transmitted to offspring. This statement confuses me. The word "only" is what confuses me . Could you please explain it? Thank you very much ! I enjoy all your lectures! very educational indeed !

Microbial Genetics

  • What is a gene?
    • Enzyme, biochemical, genetic coding definitions
  • Replication, transcription, translation, regulation
    • Induction and repression of bacterial genome
  • Mutation
    • Germline and somatic mutations
    • Causes and types of mutation
  • Bacterial Genetics
    • Gene recombination, transformation, conjugation and transduction
    • Bacterial plasmids and transposons

Microbial Genetics

Lecture Slides are screen-captured images of important points in the lecture. Students can download and print out these lecture slide images to do practice problems as well as take notes while watching the lecture.

  1. Intro
    • What is a Gene?
    • What is a Gene?
    • Genetic Code
      • Transcription and Replication
        • Replication of Bacterial DNA
        • DNA Transcription
        • Bacterial Transcription
        • Translation
        • Gene Regulation
        • Regulation of Transcription
          • Repression
            • Induction
              • Germline Mutation
              • Mutations
              • Causes of Mutations
              • Types of Mutations
              • Bacterial Gene Recombination
              • Genetic Recombination
              • Bacterial Recombination
                • Bacterial Transformation
                  • Conjugation in E. Coli
                    • Transduction by a Bacteriophage
                      • Plasmids
                      • R-Factor, A Type of Plasmid
                        • Transposons
                        • Example 1
                          • Example 2
                            • Example 3
                              • Intro 0:00
                              • What is a Gene? 0:39
                                • A Portion of the Chromosome That Determines or Affects a Single Character or Phenotype
                                • Biochemical Definition of a Gene
                                • Original Definition: One Gene-One Polypeptide
                              • What is a Gene? 1:48
                                • Regulatory Sequence
                              • Genetic Code 2:44
                              • Transcription and Replication 3:56
                              • Replication of Bacterial DNA 5:05
                                • Copy Both Sides of DNA Strand
                              • DNA Transcription 5:53
                                • DNA is Transcribed to Make RNA
                                • RNA Polymerase Binds to the Promoter Sequence
                                • Direction
                                • Transcription Stops When It Reaches the Terminator Sequence
                              • Bacterial Transcription 6:39
                                • Transcription
                                • No Nucleus
                              • Translation 7:51
                                • mRNA is Translated In Codons
                                • Translation of mRNA Begins at the Start Codon
                                • Translation Ends at Nonsense Codon
                              • Gene Regulation 8:34
                                • Constitutive Genes Are Expressed at a Fixed Rate
                                • Other Genes Are Expressed Only as Needed
                              • Regulation of Transcription 9:11
                              • Repression 10:16
                              • Induction 11:04
                              • Germline Mutation 12:09
                                • Evolutionary Biology
                                • Molecular Biology
                              • Mutations 14:34
                                • Random and Rare
                                • Can Be Beneficial or Neutral
                                • Not All Mutations Matter
                                • Somatic Mutations
                                • Germline Mutations
                              • Causes of Mutations 16:44
                                • DNA Fails to Copy Accurately
                                • External Influences Can Create Mutations
                              • Types of Mutations 18:14
                                • Substitution
                                • Examples of Substitutions
                                • Silent Mutations
                                • Insertion
                                • Deletion
                                • Frame Shift
                              • Bacterial Gene Recombination 22:16
                                • Vertical Gene Transfer
                                • Horizontal Gene Transfer
                              • Genetic Recombination 23:46
                                • Exchange of Genes Between Two DNA Molecules
                                • Crossing Over Occurs When Two Chromosomes Break and Rejoin
                                • Recipient Chromosome Contains New DNA
                              • Bacterial Recombination 24:51
                              • Bacterial Transformation 25:53
                              • Conjugation in E. Coli 28:36
                              • Transduction by a Bacteriophage 30:04
                              • Plasmids 31:53
                                • What are Plasmids?
                                • F-Factor
                                • Other Plasmids Encode for Proteins That Enhance the Pathogenicity of a Bacterium
                                • Dissimilation Plasmids
                                • R Factors
                              • R-Factor, A Type of Plasmid 33:53
                              • Transposons 35:04
                                • Move From One Region of DNA to Another
                                • Contain Insertion Sequences for Cutting and Resealing DNA (Tansposase)
                              • Example 1 36:14
                              • Example 2 37:34
                              • Example 3 38:15