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For more information, please see full course syllabus of Microbiology
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Gram Negative Bacteria

  • Introduction and General Description
    • Properties of gram negative bacteria
      • Gram negative laboratory testing algorithm
      • Outer membrane and genetic exchange
  • Immune Reaction to Gram Negative Bacteria
  • Examples of Gram Negative Bacteria
    • Review of endotoxin production
    • E coli
    • Salmonella
    • Vibrio
    • Bordetella

Gram Negative Bacteria

Lecture Slides are screen-captured images of important points in the lecture. Students can download and print out these lecture slide images to do practice problems as well as take notes while watching the lecture.

  • Intro 0:00
  • Introduction 0:29
    • Internal Cell Wall
    • Characteristic Properties
  • Gram Negative Bacterial Cell Wall 2:01
    • Outer Membrane Provides a Barrier
    • Outer Membrane Contains Lipid A
  • Properties of Gram Negative Bacteria 3:20
    • Lipid A Molecule
    • Lipopolysaccharides
    • Most Gram Negative Bacteria Do Not Form Spores
  • Gram Negative Laboratory Algorithm 4:05
  • Properties of Gram Negative Bacteria 6:45
    • Outer Membrane
    • Genetic Exchange
  • Immune Reaction to Gram Negative Bacteria 7:49
  • Examples of Gram Negative Bacteria 12:12
  • Endotoxin 12:52
    • Differ from Exotoxin in Several Ways
    • Released When Gram Negative Bacteria Undergo Lysis and Endotoxin is Liberated
    • Stimulate Macrophages to Release High Concentrations of Cytokines
  • E. Coli Bacteria 15:03
    • Escherichia Coli
    • Pathogenic Strains of E. Coli
  • Shiga-Toxin E. Coli Outbreak, Germany 2011 16:24
  • Salmonella Bacteria 18:29
    • Pathogenicity
    • Infection by Salmonella
    • Another Image of Infection by Salmonella
  • Bacterial Infections, 2013 23:44
  • Vibrio Bacteria 25:12
    • Vibrio Genus
    • Most Virulent Species is Vibrio Cholerae
  • Cholera Life Cycle 26:59
  • Worldwide Cholera Cases 29:44
  • New Cases of Cholera in Haiti During a 2 Year Period 30:24
  • Preventing Cholera Infection with Gut Flora 31:10
  • Bordetella Pertussis 32:55
    • Aerobic Coccobacillus
    • Tracheal Toxin
    • Pertussis Toxin
  • Pertussis Infection Timeline 34:25
  • Pertussis Symptom Timeline 36:10
  • Reported Pertussis Cases in US 1922-2003 37:31
  • Example 1 38:09
  • Example 2 39:36
  • Example 3 41:16