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  • Introduction to Mycobacterium tuberculosis (TB)
    • Acid fast cell wall of TB
    • TB incidence – global and United States
    • Co-infection with HIV
  • Tuberculosis Pathogenesis
    • Airborne transmission
    • Stages of infection
      • Latent TB
      • Active TB
  • Tuberculosis Testing
  • Tuberculosis Vaccination


Lecture Slides are screen-captured images of important points in the lecture. Students can download and print out these lecture slide images to do practice problems as well as take notes while watching the lecture.

  • Intro 0:00
  • Tuberculosis Introduction 0:47
    • Malaria
    • Acid-Fast Staining
    • Tuberculosis Disease
    • Latent and Active Disease
    • Strong Man Image Example
  • Mycobacterium Tuberculosis 2:39
    • Cell Wall
  • Tuberculosis Incidence in 2012 3:21
  • Worldwide Tuberculosis Incidence 4:19
  • TB Research Center, Chennai, India 5:00
  • Tuberculosis in United States 5:47
  • Estimated HIV Co-Infection Among Individuals Diagnosed with TB in U.S. 6:28
  • Tuberculosis Pathogenesis 7:40
    • Infection
    • How It's Spread
    • What Determines Whether or Not an Individual Will be Exposed
    • Bacilli can Multiply Once Reaching the Alveoli
  • Mycobacterium Tuberculosis 10:18
    • Inactive Form of TB
    • Active vs. Inactive Form of TB Depends on If Bacilli Stay in Tissue or Break Out
  • Tuberculosis Pathogenesis 11:20
    • Bacilli That Reach Alveoli
    • Those Bacilli are Ingested by Macrophages
    • No Symptoms of Disease
    • More Advanced Stage
    • Multiply in Macrophages
    • Inflammation
    • After a Few Weeks Disease Symptoms Appear
    • Caseous Center
    • Aerobic Bacilli Do Not Grow Well in the Center
    • Granuloma Can Reactivate Later
    • Active Disease: The Granuloma Can Rupture with Liquefaction
    • Active TB
  • Tuberculosis Staging 18:12
    • Stage 3 Important Stage
    • Stage 5 You Have TB
  • Tuberculosis Testing 19:31
    • Tuberculin Skin Test
    • Positive Skin Reaction Image Example
  • Tuberculosis Vaccination 20:32
    • BCG Vaccination in Other Areas Around the World
    • BCG Protects from the Active Form of Tuberculosis
    • BCG Does Not Confer Lifelong Protection
  • Mycobacterium Tuberculosis 22:51
    • Target Different Parts
    • Regiment
  • Example 1 24:34
  • Example 2 26:40