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Linked Genes and Non-Mendelian Modes of Inheritance

  • If genes are on the same chromosome they do not assort independently. Such genes are linked and may be inherited together.
  • During meiosis, crossing over occurs, which allows for recombination and greater genetic variation in the offspring.
  • A genetic linkage map depicts the relative positions of genes on a chromosome and the distances between the genes. One linkage map unit = 1% recombination frequency.
  • Some genes are found outside of the nucleus in organelles such as mitochondria and chloroplasts. These genes have a maternal pattern of inheritance.
  • Some genes are imprinted so expression only occurs for the allele inherited from the father or the allele inherited from the mother. One mechanism for genomic imprinting is DNA methylation.

Linked Genes and Non-Mendelian Modes of Inheritance

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AP Biology Intro